{"title":"Development of epidermal growth factor-polycaprolactone nanofiber mesh and bead for wound healing","authors":"Wei-Chih Lin, Chieh-Shan Wu, I. Yeh","doi":"10.1109/TRANSDUCERS.2017.7994319","DOIUrl":null,"url":null,"abstract":"The biocompatible PCL2b200 nanofibre mesh and beads containing epidermal growth factor (EGF) were fabricated separately by using our developed electrospinning and electrospray process for the tissue regeneration applications. The drug release behaviours of two fabricated EGF nano-scaffolds were characterized for 448 hours. The EGF nanofibre mesh performed the quicker released speed and higher release amount than beads. Due to the influence of released EGF, nanofibre mesh also reveals a better proliferation and cell viability than beads that was proved by using the MTT assay.","PeriodicalId":174774,"journal":{"name":"2017 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS)","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2017-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"2017 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/TRANSDUCERS.2017.7994319","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The biocompatible PCL2b200 nanofibre mesh and beads containing epidermal growth factor (EGF) were fabricated separately by using our developed electrospinning and electrospray process for the tissue regeneration applications. The drug release behaviours of two fabricated EGF nano-scaffolds were characterized for 448 hours. The EGF nanofibre mesh performed the quicker released speed and higher release amount than beads. Due to the influence of released EGF, nanofibre mesh also reveals a better proliferation and cell viability than beads that was proved by using the MTT assay.
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