C C Patrick, G Virella, J Koistinen, H H Fudenberg
{"title":"Differential binding of IgA proteins of different subclasses and allotypes to Staphylococcal protein A.","authors":"C C Patrick, G Virella, J Koistinen, H H Fudenberg","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The binding of myeloma proteins of known subclass and allotype to staphylococcal protein A has been studied using affinity chromatography with Protein A-Sepharose CL-4B. Three IgA1 proteins did not show any binding, whereas two IgA2 A2m(1) and one IgA2 A2m(2) proteins were found to bind to the column.</p>","PeriodicalId":23935,"journal":{"name":"Zeitschrift fur Immunitatsforschung. Immunobiology","volume":"153 5","pages":"466-9"},"PeriodicalIF":0.0000,"publicationDate":"1977-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zeitschrift fur Immunitatsforschung. Immunobiology","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
The binding of myeloma proteins of known subclass and allotype to staphylococcal protein A has been studied using affinity chromatography with Protein A-Sepharose CL-4B. Three IgA1 proteins did not show any binding, whereas two IgA2 A2m(1) and one IgA2 A2m(2) proteins were found to bind to the column.
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