Fetal growth

Jane E. Hirst, A. T. Papageorghiou
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Abstract

Fetal growth is a complex and highly orchestrated process. Monitoring fetal growth is one of the cornerstones of the evaluation of fetal well-being. This chapter explores the global epidemiology of poor fetal growth, the controversies around the definition of the condition, and the scientific validity of the multitude of growth charts and approaches to fetal growth currently in use around the world. In 2014, the accepted approaches to fetal growth were challenged by the findings of the international INTERGROWTH-21st Project. This major international project demonstrated that the growth of babies in utero and the size of babies around the world are remarkably similar if maternal environmental, social, and medical conditions are relatively optimal. From this study, the first standards for fetal and newborn growth have been produced. The management of babies detected to be large for gestational age (LGA) also remains controversial and a clinical challenge. With increasing rates of maternal obesity and gestational diabetes, a growing proportion of babies are born LGA or detected to be LGA in utero. Other than the treatment for gestational diabetes, the evidence for effective interventions to prevent the development of LGA during pregnancy is limited. Key issues regarding the management of LGA include the most appropriate timing and mode of delivery to prevent shoulder dystocia and birth trauma.
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胎儿生长
胎儿生长是一个复杂而高度协调的过程。监测胎儿生长是胎儿健康评估的基石之一。本章探讨了胎儿生长不良的全球流行病学,围绕该疾病定义的争议,以及目前世界各地使用的大量生长图表和胎儿生长方法的科学有效性。2014年,国际intergrowth -21项目的研究结果对公认的胎儿生长方法提出了挑战。这个重大的国际项目表明,如果母亲的环境、社会和医疗条件相对理想,世界各地婴儿在子宫内的生长和婴儿的大小是非常相似的。从这项研究中,产生了胎儿和新生儿生长的第一个标准。检测到的大胎龄(LGA)婴儿的管理也仍然存在争议和临床挑战。随着产妇肥胖率和妊娠期糖尿病的增加,越来越多的婴儿出生时患有LGA或在子宫内被检测为LGA。除了对妊娠期糖尿病的治疗外,有效干预预防妊娠期LGA发展的证据是有限的。关于LGA管理的关键问题包括最合适的分娩时间和方式,以防止肩难产和分娩创伤。
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