C. Carraher, M. Roner, P. Slawek, Francesca Mosca, J. Frank, Lindsey C. Miller
{"title":"Groups 4 and 15 and Organotin Condensation Polymers for The Treatment of Cancers and Viruses","authors":"C. Carraher, M. Roner, P. Slawek, Francesca Mosca, J. Frank, Lindsey C. Miller","doi":"10.32474/MAMS.2018.01.000103","DOIUrl":null,"url":null,"abstract":"This short review describes the use of group 4 metallocenes, group 15 organometallics and organotin polymers in the treatment of human cancer tumors and viruses. These metal-containing polymers show good inhibition of all the main group solid tumors including pancreatic, lung, brain, breast, prostate and colon human cell lines. They also show inhibition of a variety of viruses including zika, herpes and vaccinia viruses. Synthesis of the polymers is rapid employing interfacial polymerization and commercially available reactants. They offer physicians a new class of drugs for the treatment of a variety of cancers and viruses.","PeriodicalId":437994,"journal":{"name":"Modern Approaches on Material Science","volume":"37 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2018-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Modern Approaches on Material Science","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.32474/MAMS.2018.01.000103","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
This short review describes the use of group 4 metallocenes, group 15 organometallics and organotin polymers in the treatment of human cancer tumors and viruses. These metal-containing polymers show good inhibition of all the main group solid tumors including pancreatic, lung, brain, breast, prostate and colon human cell lines. They also show inhibition of a variety of viruses including zika, herpes and vaccinia viruses. Synthesis of the polymers is rapid employing interfacial polymerization and commercially available reactants. They offer physicians a new class of drugs for the treatment of a variety of cancers and viruses.