Biological Markers Study of Acute and Chronic Myeloid Leukemia

A. A. Ismaeel
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Abstract

Twenty two acute myelogenous leukemia (AML) patients and 20 chronic myelogenous leukemia (CML) patients, were admitted to Medical City Hospital, in addition to 35 healthy individuals as the control group. Vitamin C and vitamin D, trace and essential elements cobalt, and Nickel magnesium were evaluated in the sera of all above individuals, using high performance liquid chromatography and atomic absorption spectrophotometry for evaluating vitamins and elements. The results revealed a a significant decrease in vitamin C and vitamin D and Mg levels in both patients groups compared to controls and a significant difference in CO and Ni levels in sera of AML and CML was found. Conclusion: Vitamins, trace and essential elements abnormalities occur in both patient groups compared to Controls.
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急慢性髓系白血病的生物学标志物研究
选取医学城医院收治的急性髓性白血病(AML)患者和慢性髓性白血病(CML)患者各22例和20例,并以35例健康人为对照组。采用高效液相色谱法和原子吸收分光光度法测定上述受试者血清中维生素C和维生素D、微量元素钴和必需元素镍镁。结果显示,与对照组相比,两组患者的维生素C、维生素D和Mg水平显著降低,AML和CML血清中的CO和Ni水平也有显著差异。结论:与对照组相比,两组患者均出现维生素、微量元素和必需元素异常。
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