Application of Large Area Mapping AFM for Automated Structural and Mechanical Analysis of Developing Cells and Tissues

Abstract

Application of Large Area Mapping AFM for Automated Structural and Mechanical Analysis of Developing Cells and Tissues Active forces in biological systems define the interactions between single molecules, growing cells and developing tissues. Further development of novel biomaterials for tissue engineering is driven by the biomechanical and molecular cues provided to cells by their environment which are crucial parameters that influence motility, behavior, and the fate of progenitor cells.