Numerical analysis on oxygen saturation measurement by dual-wavelength optical low-coherence interferometry

Abstract

Dual-wavelength optical low-coherent interferometry is proposed in this paper to measure the oxygen saturation in human retinal blood vessel. Wavelength consideration is made from the standpoint of eye safety and system sensitivity. Principle of oxygen saturation measurement based on dual-wavelength low-coherence interferometer is thoroughly developed. Numerical simulation on interference signal versus oxygen saturation corresponding to the oxygen sensitive wavelength and the isobestic wavelength is conducted.