İntihar Amaçlı Yüksek Doz Feniramidol Hidroklorür Alımına Bağlı Karaciğer Enzim Yükselmesi

Abstract

Phenyramidol hydrochloride is a potent non-narcotic analgesic with concomitant muscle-relaxant activity that is the result of an interneuronal blocking action. Phenyramidol is conjugated in the liver with glucuronic acid and is primarily excreted as phenyramidol glucuronide in urine. Some is also excreted in feces via bile. If liver dysfunction develops in the course of phenyramidol usage, the treatment should be discontinued. We were unable to find in the literature any publication concerning overdose of phenyramidol hydrochloride – either accidental or intentional. In our case, a patient ingested 16 units of 400 mg phenyramidol hydrochloride with the intent of committing suicide. Ours is the first article to be published on the subject of phenyramidol hydrochloride overdose.