The Study of Blood Conductivity and Viscosity in Malaria

Zeinab K. Osman, Nodar O. Khalifa, Sara IB. Mustafa
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Abstract

Malaria is the most widespread disease in Africa and developing countries which has a negative effect on everyday life and causes thousands death each year. To find new, more precise, and less expensive diagnostic methods, an increasing number of studies are needed. In order to replace the conventional method for detecting the presence of malaria parasites in human blood, the electrical conductivity and viscosity of the blood of falciparum malaria were measured. To investigate the effect of malaria on physical properties; a total of hundred blood samples were collected from Khartoum state teaching hospital, samples were subdivided into two groups, fifty from the malaria patient and other fifty from healthy people setting as control group. An Ostwald viscometer, a hematocrit centrifuge and conductivity equipment were used to measure the viscosity, hematocrit and electrical conductivity of blood respectively. In this study it was found that the mean value of hematocrit for healthy individuals was 45.7%. While in malaria patients was 27.7 %, in addition, the mean value of blood viscosity for healthy individuals was 4.4 cp, while 2.8 cp, for patients.  The mean value for conductivity of whole blood in healthy individuals was 4.4 m. s, whereas it was 3.9 m.s in patients, but the mean value of serum conductivity was 4.3 in patients a m.s and 8.3 in healthy individuals. Conclusion:  The results obtained in this indicated significantly changed in viscosity, hematocrit and electrical conductivity of blood due malaria parasites. These physical changes caused by Plasmodium falciparum malaria can be used as new malaria diagnostic techniques.
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疟疾患者血液传导性和黏性的研究
疟疾是非洲和发展中国家最普遍的疾病,对日常生活产生负面影响,每年造成数千人死亡。为了找到新的、更精确的、更便宜的诊断方法,需要进行越来越多的研究。为了取代传统的检测人血中疟原虫存在的方法,测定了恶性疟血的电导率和黏度。探讨疟疾对物理性质的影响;从喀土穆州立教学医院采集血液样本共100份,样本再分为两组,50份来自疟疾患者,50份来自健康人群作为对照组。用奥斯特瓦尔德粘度计、血细胞比容离心机和电导率仪分别测定血液粘度、血细胞比容和电导率。本研究发现健康人的红细胞压积平均值为45.7%。此外,健康个体的血液粘度平均值为4.4 cp,而疟疾患者为27.7%,而患者的血液粘度平均值为2.8 cp。健康人全血电导率的平均值为4.4 m.s,而患者为3.9 m.s,而血清电导率的平均值为4.3 m.s,健康人为8.3 m.s。结论:疟原虫对血液粘度、红细胞压积和电导率有显著影响。这些由恶性疟原虫引起的身体变化可作为新的疟疾诊断技术。
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