Post Operative Cognitive Dysfunction: A Literature Review

Irfan Ferdinand Tambunan
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Abstract

Along with ages, elderly patients with comorbid who undergoing surgical procedures are more likely to experience cognitive disorders such as decreased quality of life and loss of independence. This is known as postoperative cognitive dysfunction. The percentage is quite significant for old age to experience cognitive disorders. Ages, education level, health and mental status can be a factor causing cognitive disorders. Comprehensive assessment of objective mental, social and functional status can increase patient preoperative. Perioperative pharmacological management can reduce the incidence of POCD. For example, minimal use of propofol in spinal anesthesia may reduce POCD in hip fracture surgery. The use of dexmedetomidine in ventilated patients in the ICU may also reduce POCD. The etiology is still unclear, but there is a suspicion that the use of neurotoxic anesthetics can trigger the occurrence of POCD, but this has not been further proven.
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术后认知功能障碍:文献综述
随着年龄的增长,接受外科手术的老年合并症患者更有可能出现认知障碍,如生活质量下降和丧失独立性。这被称为术后认知功能障碍。老年人出现认知障碍的比例相当大。年龄、受教育程度、健康状况和精神状态都可能是导致认知障碍的因素。对患者的客观心理、社会和功能状况进行综合评估,可以提高患者的术前评价。围手术期药物管理可降低POCD的发生率。例如,在脊柱麻醉中少量使用异丙酚可以减少髋部骨折手术中的POCD。在ICU通气患者中使用右美托咪定也可降低POCD。病因尚不清楚,但有人怀疑使用神经毒性麻醉药可引发POCD的发生,但这尚未得到进一步证实。
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