Penurunan Kualitas dan Kuantitas Spermatozoa Mencit (Mus musculus L.) Setelah Pemberian Ekstrak Rimpang Rumput Teki ( Cyperus rotundus L.)

Indriyani Indriyani, H. Busman, Sutyarso Sutyarso
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Abstract

The lack of participation of men in family planning programs is due to the limited choice of male contraceptive. Traditional medicinal plants are one of ideal alternative types of male contraception. This study aimed to study the effect of Cyperus rotundus L. rhizome on the quality and quantity of spermatozoa in male mice (Mus musculus L.). Twenty male mice were divided into four treatment groups, namely control group (C0), the dose of teki grass rhizome extract 4.5 mg/40 g BW (C1), the dose of teki grass rhizome extract 45 mg/40 g BW (C2), and the dose of teki grass rhizome extract 135 mg/40 g BW (C3) for 35 days. Parameters measured were the motility, viability, morphology, and concentration of spermatozoa. The data were analyzed for diversity and then further tested using the LSD test with a 5% significance level. The results of the analysis showed that giving teki grass rhizome extract had a significant effect on the motility, viability, morphology, and concentration of spermatozoa. It can be concluded that teki grass rhizome can be used as an alternative male contraception because it can reduce motility, viability, morphology, and spermatozoa concentration.
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精子质量和数量下降。在麦草萃取物之后。
男性缺乏参与计划生育项目的原因是男性避孕药的选择有限。传统药用植物是男性避孕的理想替代类型之一。本研究旨在研究香附根茎对雄性小鼠精子质量和数量的影响。将20只雄性小鼠分为4个治疗组,即对照组(C0)、木参提取物4.5 mg/40 g BW组(C1)、木参提取物45 mg/40 g BW组(C2)、木参提取物135 mg/40 g BW组(C3),连续治疗35 d。测量的参数包括精子的活力、活力、形态和浓度。对数据进行多样性分析,然后用5%显著性水平的LSD检验进一步检验。结果表明,给药对精子的活力、活力、形态和浓度有显著影响。结果表明,木藿香根茎可降低精子活力、活力、形态和精子浓度,可作为男性避孕的替代药物。
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