Demographic and Clinico-Pathological Profile of Gall Bladder Carcinoma Patients in a Tertiary Care Hospital in Odisha

Abstract

Background: Gall Bladder cancer ranks as sixth most common digestive tract cancer with very poor survival rate. The data from India shows a very wide variation in incidence. The purpose of this study is to determine the Demographic and Clinico- pathological Profile of Gall Bladder carcinoma patients in a tertiary care hospital in Odisha. Methods: We retrospectively analyzed 103 patients of gall bladder carcinoma from our Hospital database between 2016 and 2019. The demographic and epidemiological characteristics were analyzed. Socioeconomic status was determined by the modified Kuppuswamy’s socioeconomic scale. The clinical features were analyzed as documented by history, physical examination, and imaging features. Results: Out of 103 patients, 44 (42.7%) were males and 59 (57.3%) were females. The largest numbers of patients were seen in the age group more than 40 years of age. 46.4% of patients were in low socioeconomic status. Pain abdomen was the most common symptom in 58(56.3%) patients. There was no statistically significant association of cancer with gall stone disease. In Odisha, more gall bladder cancer was seen in females. Due to lack of awareness & poor socioeconomic status maximum patients present in advanced stage with common symptom as pain abdomen. Conclusion: Most of the patients in this study belong to lower socioeconomic classes. Females were more commonly affected from gall bladder cancer and presented at an advanced stage. In our study 37.9% Gall bladder cancer were associated with gall stone disease, though it was not statistically significant.