Support vector machine classifications for microarray expression data set

Junying Zhang, R. Lee, Y.J. Wang
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引用次数: 21

Abstract

Gene selection, cancer classification and functional gene classification are three main concerns and interests by biologists for cancer detection, cancer classification, and understanding the functions of genes from the molecular level of tissues, where the large number of genes and relatively small number of experiments in gene expression data generate a great challenge. After a brief introduction of support vector machine(SVM) for classification, this paper presents recent SVM approaches for gene selection, cancer classification and functional gene classification followed by analysis on the advantages and limitations of SVM on these applications.
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微阵列表达数据集的支持向量机分类
基因选择、癌症分类和功能基因分类是生物学家从组织分子水平上对癌症检测、癌症分类和理解基因功能的三个主要关注点和兴趣,其中基因数量多而基因表达数据实验数量相对较少,对基因表达数据产生了很大的挑战。本文在简要介绍支持向量机分类的基础上,介绍了支持向量机在基因选择、癌症分类和功能基因分类等方面的最新应用,并分析了支持向量机在这些应用中的优势和局限性。
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