N. Gofur, A. Gofur, Soesilaningtyas, Rizki Nur Rachman Putra Gofur, M. Kahdina, H. Putri
{"title":"Immunosenescence in Autoimmune Related to Periodontal Disease : A Review Article","authors":"N. Gofur, A. Gofur, Soesilaningtyas, Rizki Nur Rachman Putra Gofur, M. Kahdina, H. Putri","doi":"10.32474/IPDOAJ.2021.05.000222","DOIUrl":null,"url":null,"abstract":"Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder characterized by the development of\nautoantibodies and immune complexes associated with a variety of clinical manifestations and tissue damage. SLE is the production\nof reactive antibodies against the body’s own cells. SLE is multifactorial and most likely involves complex interactions between\ngenetic, environmental, and hormonal factors. There is an aging process in immune cells due to changes in the innate and adaptive\nimmune system compartments. This phenomenon is known as Immunosenescence, also occurs on autoimmune. One of the\ncharacteristics of elderly people is their inability to respond to vaccines and infections properly.","PeriodicalId":106996,"journal":{"name":"Interventions in Pediatric Dentistry Open Access Journal","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2021-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Interventions in Pediatric Dentistry Open Access Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.32474/IPDOAJ.2021.05.000222","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder characterized by the development of
autoantibodies and immune complexes associated with a variety of clinical manifestations and tissue damage. SLE is the production
of reactive antibodies against the body’s own cells. SLE is multifactorial and most likely involves complex interactions between
genetic, environmental, and hormonal factors. There is an aging process in immune cells due to changes in the innate and adaptive
immune system compartments. This phenomenon is known as Immunosenescence, also occurs on autoimmune. One of the
characteristics of elderly people is their inability to respond to vaccines and infections properly.
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