[Alloplasty of dura mater defects with identical tissue prepared and transported in formalin-containing gel media].

Abstract

The storage of dura mater transplants in formalin-containing gel media which allow the entire process of preparation of the biological material to be conducted in non-sterile conditions is substantiated experimentally and clinically. A formalinized allogenous tissue of the same name transplanted in experiments and in the clinic into a defect in the dura mater undergoes active reorganisation and is replaced within a year with a newly-formed connective tissue which does not differ in architectonics from the dura mater of the recipient. When transplants of the dura mater stored in formalin-containing gel media were used in the clinic (172 operations) no complications of the type of liquorrhea, prolapse of the cerebral tissue or coarse subdural adhesions were noted. Suppuration developed in 3 patients (1.7%). The cause of the suppuration, however, was not associated with the transplant. All this makes it possible to recommend allogenous transplants of dura mater stored in formalin-containing gel media for wide use in the practice.