{"title":"Characterization of a naturally occurring R plasmid in Salmonella isangi conferring unusually high resistance to ampicillin.","authors":"R Avramova, F Schmidt, B Wiedemann","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>A strain of Salmonella isangi was isolated from HUMANA milk, used a baby food in Bulgarian hospitals. It harbours two stable plasmids, distinguishable by their molecular weight of 21 Mdal for the transfer factor (rRB 1) and 9,3 Mdal for R-factor rRB 2, confering resistance to ampicillin, cephalothin, streptomycin and sulfonamides. Both plasmids are maintained in different copy numbers per chromosome genome equivalent, 8 copies for rRB 1 and 158 copies for rRB 2, associated with an unusual high level of resistance to ampicillin (MIC 65 mg/ml).</p>","PeriodicalId":23838,"journal":{"name":"Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Erste Abteilung Originale. Reihe A: Medizinische Mikrobiologie und Parasitologie","volume":"244 4","pages":"452-60"},"PeriodicalIF":0.0000,"publicationDate":"1979-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Erste Abteilung Originale. Reihe A: Medizinische Mikrobiologie und Parasitologie","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
A strain of Salmonella isangi was isolated from HUMANA milk, used a baby food in Bulgarian hospitals. It harbours two stable plasmids, distinguishable by their molecular weight of 21 Mdal for the transfer factor (rRB 1) and 9,3 Mdal for R-factor rRB 2, confering resistance to ampicillin, cephalothin, streptomycin and sulfonamides. Both plasmids are maintained in different copy numbers per chromosome genome equivalent, 8 copies for rRB 1 and 158 copies for rRB 2, associated with an unusual high level of resistance to ampicillin (MIC 65 mg/ml).
分享
京公网安备 11010802042870号
京ICP备2023020795号-1
求助内容：
应助结果提醒方式：
扫码关注我们
