Motor neurone disease and multiple sclerosis among immigrants to Britain.

G Dean, R Brady, H McLoughlin
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引用次数: 50

Abstract

Hospital discharge rates for various immigrant groups resident in Greater London and the West Midlands were studied to compare the incidence of two diseases of the nervous system-motor neurone disease (MND) and multiple sclerosis (MS). For both these conditions immigrants from Europe, Ireland, America and from the old commonwealth countries of Canada, Australia, and New Zealand had discharge rates that were similar to those for people born in the United Kingdom. In contrast, immigrants from the new commonwealth countries of Asia, Africa, America (including the West Indies), and Europe (Gibraltar, Malta, and Gozo) had a greatly reduced risk of MS but a very similar risk of MND compared with those born in the United Kingdom. MS but not MND was rare among immigrants of Asian or African ethnic origin and uncommon among immigrants from the West Indies. Deaths attributed to MS and MND have also been studied. During a three-year period there were no deaths reported for MS among immigrants of Asian and African ethnic origin and 14 were expected. There were two deaths from MND among these immigrants and five were expected. Among the immigrants from the West Indies two deaths were attributed to MS and 13 were expected, and there were three deaths attributed to MND and four were expected. The contrast between MND and MS in hospital morbidity and mortality confirms that MS among immigrants to Britain is rare in those of Asian and African ethnic origin.

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英国移民的运动神经元疾病和多发性硬化症
研究了居住在大伦敦和西米德兰兹的不同移民群体的出院率,以比较神经系统-运动神经元疾病(MND)和多发性硬化症(MS)两种疾病的发病率。在这两种情况下,来自欧洲、爱尔兰、美国以及来自加拿大、澳大利亚和新西兰等旧英联邦国家的移民的出院率与出生在英国的人相似。相比之下,来自亚洲、非洲、美洲(包括西印度群岛)和欧洲(直布罗陀、马耳他和戈佐岛)的新英联邦国家的移民患多发性硬化症的风险大大降低,但与出生在英国的移民相比,患MND的风险非常相似。多发性硬化症在亚洲或非洲裔移民中很少见,在西印度群岛移民中也不常见。MS和MND导致的死亡也被研究过。在三年期间,亚洲和非洲族裔移民中没有MS死亡报告,预计有14例。这些移民中有两人死于MND,预计会有五人死亡。在来自西印度群岛的移民中,有两人死于多发性硬化症,预计有13人死于多发性硬化症,有三人死于多发性硬化症,预计有4人死于多发性硬化症。MND和MS在医院发病率和死亡率的对比证实了MS在亚洲和非洲裔移民中是罕见的。
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