Selective screening for cervical cancer. Experience of the Finnish mass screening system.

M Hakama, E Pukkala
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引用次数: 18

Abstract

Names of women eligible to be screened for cervical cancer are taken from the national population registry and the women are invited by a personal letter. The data, from these mass screenings are analysed and stored at the screening registry. To reduced the costs of the system and to increase the yield of preinvasive lesions the idea of selective screening was considered. Tt was decided that if people were selected according to their risk factors, as recorded in the national population registry, the screening would be ineffective as many cases of invasive cancer were found in the low risk groups. High risk factors were determined from anamnestic data on systems and from previous cytological diagnoses. The proportion of women with symptoms of bleeding or the class II-V smears without positive histological results constituted fewer than 10% of the participants, but 20% and 40% respectively of invasive carcinomas were found in these groups during the subsequent follow-up period. Thus it is suggested that selective screening apart from that based on age has a limited application and should be restricted mainly to the interval between the organised screenings, which in Finland is five years.

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子宫颈癌选择性筛检。芬兰大规模筛查系统的经验。
有资格接受子宫颈癌筛查的妇女的姓名从国家人口登记处获得,并通过私人信函邀请妇女。对这些大规模筛查的数据进行分析并存储在筛查登记处。为了降低系统的成本和增加侵袭前病变的产量,考虑了选择性筛查的想法。人们认为,如果根据国家人口登记处记录的风险因素来选择人们,那么筛查将是无效的,因为许多侵袭性癌症病例是在低风险群体中发现的。根据系统的记忆数据和以前的细胞学诊断确定高危因素。有出血症状或II-V级涂片无阳性组织学结果的妇女比例不到参与者的10%,但在随后的随访期间,这些组中分别发现了20%和40%的浸润性癌。因此,有人建议,除了基于年龄的选择性筛查外,选择性筛查的应用范围有限,应主要限制在有组织筛查的间隔时间内,芬兰的间隔时间为5年。
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