Associations between housing conditions, smoking habits and ventilatory lung function in men with clean jobs.

F V Rasmussen, L Borchsenius, J B Winsløw, E R Ostergaard
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Abstract

In 218 men, who had minimal occupational exposure to dusts, fumes, temperature variability, or physical exercise, the relation between housing conditions throughout life and lung function was analysed. The number of years spend in dwellings without central heating was significantly inversely associated with the level of FEV1 and MMEF, and significantly directly associated with closing capacity in per cent of TLC, CC%. Significant dose-response relationships between smoking habits and FEV1, MMEF, CC% and slope of the alveolar plateau (phase III) were found, whereas closing volume, CV%, was only correlated to age. The association between dwelling conditions and ventilatory capacity was independent of smoking habits. Tobacco smoking, however, moderated the association in as much as it was strengthened after standardisation for tobacco consumption. These data support the hypothesis that poor dwelling conditions during childhood and adolescence are associated with development of peripheral airways disease and expiratory airflow obstruction at middle age, and that comparisons of lung function between different occupational categories are incomplete and may be misleading if lifelong housing conditions or other factors reflecting socio-economic status are not taken into consideration.

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清洁工作男性住房条件、吸烟习惯和通气肺功能之间的关系。
研究人员对218名男性进行了研究,这些男性的职业暴露在粉尘、烟雾、温度变化或体育锻炼的环境中,他们一生的居住条件与肺功能之间的关系进行了分析。在没有集中供暖的住宅中花费的年数与FEV1和MMEF的水平显着负相关,并且与TLC百分比的关闭容量显着直接相关,CC%。吸烟习惯与FEV1、MMEF、CC%和肺泡平台坡度(III期)之间存在显著的剂量-反应关系,而闭合容积CV%仅与年龄相关。居住条件和通风量之间的关系与吸烟习惯无关。然而,吸烟缓和了这种联系,因为烟草消费标准化后这种联系得到了加强。这些数据支持了以下假设:儿童和青少年时期恶劣的居住条件与中年时周围气道疾病和呼气气流阻塞的发展有关;如果不考虑终身居住条件或其他反映社会经济地位的因素,不同职业类别之间肺功能的比较是不完整的,可能会产生误导。
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