M J Larsen, F Melsen, L Mosekilde, M S Christensen
{"title":"Effects of a single dose of fluoride on calcium metabolism.","authors":"M J Larsen, F Melsen, L Mosekilde, M S Christensen","doi":"10.1007/BF02013258","DOIUrl":null,"url":null,"abstract":"<p><p>Fluoride 27 mg was given perorally to 14 subjects. It was found that the serum fluoride concentration increased followed by a decrease to normal levels during 24 h. Serum concentrations of calcium and phosphate decreased initially whereas those of serum immunoreactive parathyroid hormone increased. After 24 h the measured quantities were within normal limits. The results are discussed with reference to mineralization of hard tissues and to fluoride treatment of osteoporotic patients.</p>","PeriodicalId":9389,"journal":{"name":"Calcified Tissue Research","volume":"26 3","pages":"199-202"},"PeriodicalIF":0.0000,"publicationDate":"1978-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02013258","citationCount":"5","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Calcified Tissue Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/BF02013258","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 5
Abstract
Fluoride 27 mg was given perorally to 14 subjects. It was found that the serum fluoride concentration increased followed by a decrease to normal levels during 24 h. Serum concentrations of calcium and phosphate decreased initially whereas those of serum immunoreactive parathyroid hormone increased. After 24 h the measured quantities were within normal limits. The results are discussed with reference to mineralization of hard tissues and to fluoride treatment of osteoporotic patients.