In vitro demonstration of cytotoxic antibodies and their possible role in corneal graft rejections.

Investigative ophthalmology Pub Date : 1976-06-01
P S Binder, J W Chandler, H E Kaufman
{"title":"In vitro demonstration of cytotoxic antibodies and their possible role in corneal graft rejections.","authors":"P S Binder,&nbsp;J W Chandler,&nbsp;H E Kaufman","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Rabbit corneas were exposed to heterologous guinea pig anti-rabbit antibodies in the presence of complement and cytotoxic damage to the endothelium was demonstrated using para nitroblue tetrazolium. The possible role of such antibodies as \"blocking antibodies\" and as cytotoxic antibodies in the corneal graft rejection process are discussed.</p>","PeriodicalId":14844,"journal":{"name":"Investigative ophthalmology","volume":"15 6","pages":"481-4"},"PeriodicalIF":0.0000,"publicationDate":"1976-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Investigative ophthalmology","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Rabbit corneas were exposed to heterologous guinea pig anti-rabbit antibodies in the presence of complement and cytotoxic damage to the endothelium was demonstrated using para nitroblue tetrazolium. The possible role of such antibodies as "blocking antibodies" and as cytotoxic antibodies in the corneal graft rejection process are discussed.

分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
细胞毒性抗体的体外证明及其在角膜移植排斥反应中的可能作用。
在补体存在的情况下,兔角膜暴露于异源豚鼠抗兔抗体,并使用对硝基蓝四氮唑证明内皮细胞毒性损伤。讨论了这些抗体作为“阻断抗体”和细胞毒性抗体在角膜移植排斥过程中的可能作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
A new technique for the vital staining of the corneal endothelium. Niemann-Pick disease-like inclusions caused by a hypocholesteremic agent. Experimental disciform edema and necrotizing keratitis in the rabbit. Immunofluorescent studies on the trabecular meshwork in open-angle glaucoma. A randomized technique of constant-pressure infusion.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1