Bound and free light chains in subacute sclerosing panencephalitis and multiple sclerosis serum and cerebrospinal fluid.

F Bollengier, A Lowenthal, W Henrotin
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引用次数: 34

Abstract

The kappa-lambda light chain ratios, the presence of free light chains and the double ring formation, with antikappa and antilambda serum, in single radial immunodiffusion were investigated in serum and cerebrospinal fluid of patients with subacute sclerosing panencephalitis. Cerebrospinal fluid samples of several multiple sclerosis cases were considered simultaneously. The results obtained suggest special immunoglobulin synthesis in both diseases.

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亚急性硬化性全脑炎和多发性硬化血清和脑脊液中的结合和游离轻链。
研究了亚急性硬化性全脑炎患者血清和脑脊液单径向免疫扩散中kappa-lambda轻链比、游离轻链的存在及抗kappa和抗lambda血清双环的形成。同时考虑多例多发性硬化症患者的脑脊液样本。结果表明,这两种疾病都有特殊的免疫球蛋白合成。
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