[Healing of meningo-cerebral wounds with a combination of plastic repair and hydrocortisone therapy under clinical and experimental conditions].

Abstract

An analysis of 192 experiments has demonstrated that layer-wise plastic repair of osteal-meningeal cerebral injuries helps layer-wise reparation of individual tissues, since the implants serve as guiding membranes for the healing of individual layers of the brain and scull. Hydrocortisone therapy diminishes the development of gross collagen fibers, and causes the formation of a loose glial scar from a wide-looped network of processes of fibrill-forming astrocytes; 127 clinical observations of hydrocortisone therapy with layer-wise plastic repair of the brain and scull, followed-up for to 10 years, demonstrated that this method favours the prevention of epilepsy.