Alcoholics and high-low sensory input: a pilot study.

Diseases of the nervous system Pub Date : 1977-09-01
A M Ludwig, A Wikler, R B Cain, M Buchsbaum, G Rinsky, R Taylor
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Abstract

It is hypothesized that alcoholics possess a perceptual-neurophysiological sensitivity which renders them vulnerable to the effects of information or stimulus overload: the resort to alcohol, therefore, may represent an adaptive attempt to restore physiologic homeostasis through the pharmacologic "dampening" properties of this drug. Twelve alcoholic subjects were assigned to three different levels of audio-visual sensory stimulation (no, medium, high) and three different doses of alcohol (placebo, low, high) according to a balanced incomplete block design. The results indicated trend level and significant interactions between alcohol and sensory level effects on craving intensity and systolic blood pressure, respectively, as well as a number of other intriguing findings. Should the findings of this pilot study be replicated, they will have important implications for the understanding of alcoholism.

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酗酒者和高低感觉输入:一项初步研究。
据推测,酗酒者具有一种感知神经生理敏感性,这使得他们容易受到信息或刺激过载的影响:因此,诉诸酒精可能代表了一种适应性尝试,通过这种药物的药理学“抑制”特性来恢复生理稳态。12名酗酒者被分配到三种不同水平的视听感官刺激(无、中、高)和三种不同剂量的酒精(安慰剂、低、高),根据平衡的不完全块设计。结果表明,酒精和感官水平对渴望强度和收缩压的影响分别具有趋势水平和显著的相互作用,以及许多其他有趣的发现。如果这项初步研究的结果被复制,它们将对理解酒精中毒具有重要意义。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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