Module of cellular networks in saccharomyces cerevisiae

Yueying Yang, Di Liu, Jun Meng
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Abstract

The focus of the network of research is to determine their community or module, it helps the functional organization and evolution of the network. Modular can be seen as a function of a dynamic cell system executing complex functions in a living cell. How to identify the precious knowledge resources to build a more reliable module is still one of the most important and difficult problems in bioinformatics. We put forward a state space model combining the topological method to describe the time and space module in the cell cycle of the process. Not only our module function sets of genes related to identify a condition to activate or suppress in the cell cycle process in S.cerevisiae, but also have many different solutions, which have evolved into different molecular components will be the assembly at the right time in the cell cycle. The resulting module mapping analysis showed several assumptions connection biological process to a particular cell cycle conditions.
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酿酒酵母菌的细胞网络模块
网络研究的重点是确定其社区或模块,这有助于网络的功能组织和演化。模块化可以看作是动态细胞系统在活细胞中执行复杂功能的功能。如何识别宝贵的知识资源,构建更可靠的模块仍然是生物信息学中最重要和最困难的问题之一。提出了一种结合拓扑方法的状态空间模型来描述过程中细胞周期的时间和空间模块。我们的模块功能集不仅与识别酵母细胞周期过程中激活或抑制条件相关的基因有关,而且还有许多不同的解决方案,这些解决方案已演变成不同的分子组分将在细胞周期的正确时间组装。由此产生的模块映射分析显示了几个将生物过程与特定细胞周期条件联系起来的假设。
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