Overview and study focuses of microfluidic-based cell culture systems

Manguo Huang, S. Fan, Weiwei Xing
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引用次数: 2

Abstract

Microfluidic platforms are microfabricated tools that are gaining popularity for studying of cellular biology. These platforms can allow precise control of the environment surrounding individual cells and have achieved amazing progress in application to cell culture in recent years. In this paper, we discuss the major characteristics of microfluidic chip and the corresponding advantages for cell culture, review microfluidic cell culture systems that are classified into: (i) micropatterned cell culture on substrate surface; (ii) microchannels cell culture; and, (iii) microchambers cell culture. We also introduce several study focuses of microfluidic cell culture systems.
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基于微流体的细胞培养系统综述及研究重点
微流控平台是一种微型制造工具,在细胞生物学研究中越来越受欢迎。这些平台可以精确控制单个细胞周围的环境,近年来在细胞培养中的应用取得了惊人的进展。本文讨论了微流控芯片的主要特点及其在细胞培养方面的优势,综述了微流控细胞培养系统分为:(1)底物表面微图案细胞培养;(ii)微通道细胞培养;(三)微室细胞培养。介绍了微流体细胞培养系统的几个研究热点。
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