Changes In Glutamic Oxaloacetic Transaminase Serum (SGOT) and Glutamic Pyruvic Transaminase Serum (SGPT) Value In Laparoscopic Cholecystectomy Patient at USU Hospital

Aziizah Gita, Adi Muradi Muhar
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引用次数: 1

Abstract

Background. Laparoscopic cholecystectomy has become more widely used choice compared to laparotomy cholecystectomy. Laparoscopic cholecystectomy has now become the gold standard of abdominal surgery for abdominal surgery for gallbladder abnormalities, more than 90% of patients with gallstone disease are treated surgically by laparoscopy, but several studies have revealed an increase in SGOT &SGPT values in these surgical procedures. SGPT itself occurs due to the procedure of laparoscopy. In the procedure, there is a temporary increase in the pneumoperitoneum, the pressure on the pneumoperitoneum and its duration affect the severity of ischemia by causing an increase in this liver enzyme. Among several studies, one of them revealed that at 48 hours after laparoscopic cholecystectomy surgery an enzyme increase. Objective. The purpose of the study, this research was conducted to see the changes in SGOT & SGPT values in laparoscopic cholecystectomy surgery. Method. This research method is analytic with cross sectional study design conducted at North Sumatera University Hospital. This research was conducted by looking at secondary data, namely the medical record of patients with gallstones who underwent laparoscopic cholecystectomy surgery from January 2019 to November 2019. The sample was selected by using total sampling method. Data were then analyzed using statistical application software. The number of samples was 45 samples with a diagnosis of gallstones who performed laparoscopic cholecystectomy. Results. Wilcoxon test results showed a significant change between SGOT and SGPT levels before performing operations with SGOT and SGPT levels after surgery with p=0.000 (p<0,05). Conclusion. There are changes in SGOT & SGPT in laparoscopic cholecystectomy.
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USU医院腹腔镜胆囊切除术患者血清谷草转氨酶(SGOT)和谷丙转氨酶(SGPT)的变化
背景。与开腹胆囊切除术相比,腹腔镜胆囊切除术已成为更广泛应用的选择。腹腔镜胆囊切除术现已成为腹部手术治疗胆囊异常的金标准,90%以上的胆结石患者采用腹腔镜手术治疗,但多项研究表明,在这些手术过程中,SGOT和sgpt值有所增加。SGPT本身是由腹腔镜手术引起的。在手术过程中,气腹暂时增加,气腹上的压力及其持续时间通过引起这种肝酶的增加来影响缺血的严重程度。在几项研究中,其中一项研究显示,在腹腔镜胆囊切除术后48小时,酶增加。目标。本研究的目的是观察腹腔镜胆囊切除术中SGOT和SGPT值的变化。方法。本研究方法采用横断面研究设计,在北苏门答腊大学医院进行分析。本研究是通过查看次级数据,即2019年1月至2019年11月接受腹腔镜胆囊切除术的胆结石患者的病历进行的。采用全抽样法选取样本。然后用统计应用软件对数据进行分析。样本数量为45例诊断为胆结石并行腹腔镜胆囊切除术的样本。结果。Wilcoxon检验结果显示,术前SGOT、SGPT水平与术后SGOT、SGPT水平差异有统计学意义,p=0.000 (p< 0.05)。结论。腹腔镜胆囊切除术中SGOT和SGPT的变化。
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