Corneal glycogen synthesis. I. Evidence for a gluconeogenic pathway in beef cornea.

Investigative ophthalmology Pub Date : 1976-07-01
S Andrews
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Abstract

Beef eye anterior chambers were perfused with media containing radiolabeled glycogen precursors. Incorporation of 14C from 1-alanine-U-14C into corneal epithelium glycogen suggested the presence of a gluconeogenic pathway in the eye. Failure to isolate radioactive glucose from 1-alanine-U-14C-containing perfusate after passage through the anterior chamber strongly suggests a corneal site for this pathway.

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角膜糖原合成。牛肉角膜糖异生途径的证据。
牛眼前房灌注含有放射性标记糖原前体的介质。来自1-丙氨酸- u -14C的14C掺入角膜上皮糖原表明眼睛中存在糖异生途径。通过前房后,不能从含1-丙氨酸- u - 14c的灌注液中分离出放射性葡萄糖,强烈提示该途径存在于角膜部位。
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A new technique for the vital staining of the corneal endothelium. Niemann-Pick disease-like inclusions caused by a hypocholesteremic agent. Experimental disciform edema and necrotizing keratitis in the rabbit. Immunofluorescent studies on the trabecular meshwork in open-angle glaucoma. A randomized technique of constant-pressure infusion.
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