[Effect of a new hypoglycemic drug on the blood sugar in rats].

Revista iberica de endocrinologia Pub Date : 1976-03-01
S Perán, A M De Diego, F Arcas, A Maté, M Morell
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Abstract

A sesquiterpenic lactone has been isolated from an extract of Artemisia cannariensis Lee by Clark's method and column chromatography. The hypoglycemic effects of the drug have been assayed in rats, as compared to different doses of insulin and a known sulphonylures drug. The subatance, which has been identified as vulgarine by professor Gonzalez, has highly significant hypoglycemic effects when administered orally or intravenously in relation to glycemia curves of rats previously injected with saline.

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[一种新型降糖药对大鼠血糖的影响]。
用克拉克法和柱层析法从加那利蒿提取物中分离出一种倍半萜内酯。与不同剂量的胰岛素和一种已知的磺胺类药物相比,这种药物的降糖效果已经在大鼠身上进行了分析。这种物质被冈萨雷斯教授鉴定为普通碱,与先前注射生理盐水的大鼠的血糖曲线相比,口服或静脉注射具有高度显著的降糖作用。
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