A Giant Metastatic Adrenal Cortical Carcinoma Case Presented with Rapid Progression

Merve Durna, A. Topçu, I. Yurtsever, M. Şimşek, M. Aydın, M. Seker
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Abstract

Adrenocortical carcinoma (ACC) is an uncommon and aggressive tumor. Despite the current treatment options commonly used in ACC, the prognosis is poor. No risk factors have been identified except for genetic predisposition. The most important factors affecting the prognosis are the stage at the time of diagnosis and the resectability of the primary tumor. Here, we present a metastatic ACC case of a 29-year-old woman presented with symptoms of swelling in her feet, abdominal striae, and mild abdominal pain for three months. The abdominal computed tomography scan revealed a 14 cm mass in the right adrenal gland, indistinguishable from the liver and right kidney. Clinicians should consider primary ACC, which has limited treatment options, in the differential diagnosis in the presence of findings such as edema, obesity, and striae.
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一例进展迅速的巨大转移性肾上腺皮质癌
摘要肾上腺皮质癌是一种罕见的侵袭性肿瘤。尽管目前ACC常用的治疗方案,但预后较差。除遗传易感性外,未发现其他危险因素。影响预后的最重要因素是诊断时的分期和原发肿瘤的可切除性。在此,我们报告一名29岁女性的转移性ACC病例,其症状为足部肿胀、腹部纹和轻度腹痛三个月。腹部计算机断层扫描显示右肾上腺有一个14厘米的肿块,与肝脏和右肾脏难以区分。临床医生在鉴别诊断中应考虑原发ACC,其治疗选择有限,如水肿、肥胖和条纹。
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