Prospective study of percutaneous bone-anchored implants in transfemoral amputees: Brain-machine platform technology for external prosthetic control and feedback

Abstract

Osseointegration, which describes the direct biological connection between bone and metal, has emerged as a promising method of increasing function and mobility in amputees. This technology holds significant potential, including the ability to harness an integrated neuromuscular interface to allow for volitional motor and sensory control of an external neural prosthesis. While orthopaedic osseointegration has been underway internationally for many years with a variety of implant systems, the practice is still in its early phases in the United States. Here we present the early outcomes of the first American trial for the Osseoanchored Prosthesis for the Rehabilitation of Amputees (OPRA). Our study demonstrates that one year following osseointegration, patients experience a significant improvement in function and health-related outcomes.