Gender-Specific Effects of Health and Lifestyle Markers on Individual BrainAGE

K. Franke, M. Ristow, Christian Gaser
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引用次数: 6

Abstract

This study quantifies the effects of health and lifestyle markers on individual brain aging in dementia-free elderly subjects, revealed by a relevance vector regression approach. In males, markers of metabolic syndrome as well as alcohol abuse were significantly related to increased Brain AGE scores of up to 9 years. In females, markers of healthy liver and kidney functions and an adequate supply of nutrients were significantly related to decreased Brain AGE scores.
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健康和生活方式标记对个体脑年龄的性别特异性影响
本研究量化了健康和生活方式标志物对无痴呆老年受试者个体大脑衰老的影响,揭示了相关向量回归方法。在男性中,代谢综合征的标志物和酒精滥用与大脑年龄评分的增加显著相关,最长可达9岁。在女性中,健康的肝肾功能标记物和充足的营养供应与降低的脑AGE评分显著相关。
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