Electrophysiological effects of triiodothyronine and propranolol.

J J Straumanis, C Shagass
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引用次数: 3

Abstract

The effects of triiodothyronine (T3), T3 combined with propranolol, and propranolol alone on somatosensory evoked responses (SER) and EEG were studied in 2 groups each of 6 male volunteer subjects. The following results were obtained: (1) T3 increased SER amplitude during the first 100 ms after stimulus. (2) Addition of propranolol eliminated the SER amplitude increase resulting from T3 administration. (3) Neither T3 nor T3 plus propranolol significantly altered the mean level or the temporal variability of EEG amplitude and frequency. (4) There were no significant effects of propranolol alone on SER and EEG measures.

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三碘甲状腺原氨酸和心得安的电生理效应。
研究三碘甲状腺原氨酸(T3)、T3联合心得安、心得安单用对躯体感觉诱发反应(SER)和脑电图的影响,每组6名男性志愿者。结果表明:(1)刺激后的前100 ms, T3增加了脑丝氨酸反应的幅值。(2)普萘洛尔的加入消除了T3给药引起的SER振幅升高。(3) T3和T3加心得安均未显著改变脑电图振幅和频率的平均水平和时间变异。(4)普萘洛尔单独用药对脑电、SER指标无显著影响。
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