Everyday Life Tremor Signal Processing in PD Patients using BSN

Joseph Babayan, Markus Lueken, Arun Berking, A. Pickartz, K. Reetz, F. Holtbernd, S. Leonhardt, C. Ngo
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Abstract

Parkinson’s disease is a neurological disorder characterized by the deficiency of dopamine levels in the brain. More than 75 percent of these patients suffer from tremors. Parkinsonian tremor (PT) is more characterized to be a rest tremor, but some patients suffer from action tremor as well. Usually, patients suffering from this disease are diagnosed by their physicians who perform some battery MDS-UPDRS tasks to determine the disorder. Some sensors were used to diagnose the tremor objectively, but in this study, we are using a new Body Sensor Network (BSN) designed at our institute to be used in detecting the acceleration, gyroscope, and magnetometer of the tremor patients in the clinic. Signal processing of the recorded data is performed to determine and classify the number of times throughout the day the patient suffered from tremors. This is ensured through automatic signal segmentation, extraction of several signal features, and classification with the most accurate machine learning classifier. In this study, we have proved that our BSN sensor is capable of helping clinicians in classifying tremor occurrence in Parkinson diseased patients specifically, and tremor patients generally throughout monitoring their everyday life activities.
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BSN在PD患者日常生活震颤信号处理中的应用
帕金森氏症是一种以大脑多巴胺水平缺乏为特征的神经系统疾病。这些患者中超过75%患有震颤。帕金森震颤(PT)以静止性震颤为特征,但也有一些患者伴有活动性震颤。通常,患有这种疾病的患者是由他们的医生进行一些电池MDS-UPDRS任务来确定疾病的诊断。一些传感器被用于客观诊断震颤,但在本研究中,我们正在使用我们研究所设计的新的身体传感器网络(BSN),用于检测临床震颤患者的加速度,陀螺仪和磁力计。对记录的数据进行信号处理,以确定和分类患者全天遭受震颤的次数。这是通过自动信号分割,提取多个信号特征,并使用最准确的机器学习分类器进行分类来确保的。在本研究中,我们证明了我们的BSN传感器能够帮助临床医生对帕金森病患者的震颤发生进行特异性分类,并通过监测震颤患者的日常生活活动来帮助临床医生对震颤患者进行分类。
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