3D visualization method for whole genome alignment

Da-Young Lee, Kyung-Rim Kim, Han-Ho Kim, H. Tak, Hwan-Gue Cho
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引用次数: 1

Abstract

Many biologists check and analyze the result of alignment directly for various purpose. The more we get the genome data easily, the more alignment result that needed to be analyzed increase. The new proposed visualization model for alignment sequence is designed to reveal the base sequence of alignment result, which is 3d random walk plot model, developed as Web-GL based Web system. Using this model, we can represent the contents of alignment sequence directly that it couldn't be displayed by previous visualization model, and identify diametrically different alignment sequences although their alignment score are much similar to each other. As a result, we can intuitively express the information of alignment analysis in various angle that it cannot be covered by previous alignment visualization model.
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全基因组比对的三维可视化方法
许多生物学家为了各种目的直接检查和分析校准结果。我们越容易获得基因组数据,需要分析的比对结果就越多。基于Web- gl的Web系统,设计了新的定位序列可视化模型,以显示定位结果的基本序列,即三维随机游走图模型。利用该模型,我们可以直接表示以往可视化模型无法显示的比对序列内容,并且可以识别出截然不同的比对序列,尽管它们的比对评分非常相似。因此,我们可以直观地从各个角度表达以往的对齐可视化模型所不能涵盖的对齐分析信息。
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