Development of a LSO based quality check procedure for the microPET/spl reg/ animal scanner

C. Knoess, S. Siegel, D. Newport, R. N. Goble, K. Wienhard, W. Heiss
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Abstract

In Positron Emission Tomography (PET) hardware problem of the detector system could result in image degradation or image artifacts. Therefore a quality check (QC) procedure is needed to identify defective photomultipliers (PMTs) or electronic components while using the scanner in routine studies. For the microPET/spl reg/ animal scanner no built-in transmission source is available to perform quality scans with reproducible conditions. Therefore the use of the natural radioactive background of the scintillator material LSO was intuitive for the realization of a QC. A QC for the microPET/spl reg/ system was developed. Initial values of relative detector crystal sensitivities are measured in an initial measurement. Sensitivity values in subsequent measurements are compared to the initial values. A logfile is generated, which informs the user about changes in detector sensitivities. The quality check was implemented for a microPET/spl reg/ R4 scanner. Around 1.5 /spl times/ 10/sup 6/ single counts per detector block can be acquired in a 200-800 keV energy window during a 1800 s scan. Differences in crystal sensitivities yield information about drop outs of PMTs or electronic components. Therefore hardware problems can be easily detected without the use of an additional phantom or line source. In addition, the validity of the detector setup and normalization can be tested. This will avoid image artifacts and resolution degradation.
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microPET/spl reg/动物扫描仪基于LSO质量检查程序的开发
在正电子发射断层扫描(PET)中,检测系统的硬件问题可能导致图像退化或伪影。因此,在常规研究中使用扫描仪时,需要质量检查(QC)程序来识别有缺陷的光电倍增管(pmt)或电子元件。对于microPET/spl reg/动物扫描仪,没有内置的传输源可用于在可重复的条件下进行高质量的扫描。因此,利用天然放射性本底的闪烁物质LSO直观地实现了质控。研制了微型pet /spl reg/系统的质量控制系统。在初始测量中测量相对探测器晶体灵敏度的初始值。随后测量的灵敏度值与初始值进行比较。生成一个日志文件,通知用户探测器灵敏度的变化。对microPET/spl reg/ R4扫描仪进行了质量检查。在1800秒扫描期间,在200-800 keV能量窗口中,每个检测器块可以获得约1.5 /spl次/ 10/sup / 6次的单次计数。晶体灵敏度的差异产生了pmt或电子元件脱落的信息。因此,硬件问题可以很容易地检测,而无需使用额外的幻像或线源。此外,还可以测试检测器设置和归一化的有效性。这将避免图像伪影和分辨率下降。
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