Locally Delivered Tetracycline Fibres in the Treatment of Chronic Periodontitis

Shristi Kafle, S. Pradhan, Sujaya Gupta
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引用次数: 4

Abstract

Background: Chronic periodontitis is a highly prevalent and recurrent form of periodontal disease and locally delivered tetracycline fibres are considered to exert tremendous benefits for its treatment. Aim: The aim of the study was to observe the clinical results of locally delivered tetracycline fibres in the treatment of chronic periodontitis. Materials and Methods: Patients aged 35-54 years diagnosed with chronic periodontitis of both gender fulfilling the inclusion criteria were selected. A sample size of 30 was calculated and total number of 60 posterior sites were selected. These sites were divided into two sets in a split mouth design as control sites treated with SRP alone and test sites treated with SRP plus tetracycline fibres. Results: A combination of scaling, root planing and local drug delivery in the form of tetracycline fibres resulted in added benefits in the control of chronic periodontitis on the basis of the clinical findings from this study. Conclusion: This study further adds to the evidence that tetracycline fibres as locally delivered agent are safe and effective adjunct to scaling and root planing, and can produce significant clinical benefits when compared to scaling and root planing alone in the treatment of chronic periodontitis.
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局部输送四环素纤维治疗慢性牙周炎
背景:慢性牙周炎是一种高度流行和复发的牙周病,局部输送四环素纤维被认为对其治疗具有巨大的益处。目的:观察局部给药四环素纤维治疗慢性牙周炎的临床效果。材料与方法:选择年龄在35 ~ 54岁,男女均符合入选标准的慢性牙周炎患者。计算样本量为30个,共选择60个后验位点。采用裂口设计将这些位点分为两组,分别为单独用SRP处理的对照位点和用SRP加四环素纤维处理的试验点。结果:根据本研究的临床结果,刮除、牙根刨平和四环素纤维形式的局部药物输送相结合,在控制慢性牙周炎方面产生了额外的好处。结论:本研究进一步证明,四环素纤维作为局部给药剂是安全有效的刮治和牙根刨平辅助剂,与单独刮治和牙根刨平相比,在治疗慢性牙周炎方面可以产生显著的临床效益。
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