“Surgical management of unusual large tophi in chronic tophaceous gout: A case report”

A. S. S., R. R, K. Chaudhari
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Abstract

Gout is a disorder of purine metabolism a form of inflammatory arthritis characterized by recurrent attacks of a red, tender, hot, and swollen joint. Pain typically comes on rapidly, reaching maximal intensity in less than twelve hours. The first metatarsophalangeal joint is affected in about half of cases. It may also result in tophi, renal stones, or urate nephropathy. Commonly, but very large tophi are unusual in chronic gout. Here we present 52 years male patient presenting with unusually large tophi over bilateral foot, with raised serum uric acid levels. In a untreated cases of chronic gout, patients can develop severe destructive poly articular involvement and tophi. Treatment aims at control of serum uric acid levels which can cause regression of tophi. And surgical excision of very large tophi.
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慢性痛风异常大痛风石的外科治疗1例
痛风是一种嘌呤代谢紊乱,是炎症性关节炎的一种形式,其特征是关节反复出现红、痛、热和肿胀。疼痛通常来得很快,在不到12小时内达到最大强度。大约一半的病例会影响第一跖趾关节。它也可能导致痛风、肾结石或尿酸肾病。通常,但非常大的痛风是罕见的慢性痛风。在此,我们报告52岁男性患者,表现为双侧足部异常大的痛风,血清尿酸水平升高。在未经治疗的慢性痛风的情况下,患者可发展严重的破坏性多关节受累和痛风。治疗的目的是控制血清尿酸水平,因为尿酸水平会导致痛风的消退。手术切除很大的痛风石。
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