1d Virus transmission by virus-inactivated plasma products

PhD Hannelore Willkommen (Head, Section of Viral Safety)
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引用次数: 2

Abstract

The viral safety of virus-inactivated plasma products has been markedly enhanced by the improvement in tests for screening donations and by the improvement in techniques for manufacture of plasma derivatives including methods for virus inactivation. Nevertheless, there remains a weakness in removing inactivating heat-resistant non-enveloped viruses, such as parvovirus B19. Manufacturers' efforts should continue to be concentrated on this challenge.

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1d病毒灭活血浆产物的病毒传播
病毒灭活血浆产品的病毒安全性已因供体筛选试验的改进和血浆衍生物制造技术(包括病毒灭活方法)的改进而显著提高。然而,在清除灭活耐热非包膜病毒(如细小病毒B19)方面仍然存在弱点。制造商应继续集中精力应对这一挑战。
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