TO THE QUESTION OF THE CARDIOVASCULAR RISK FACTORS IN MEN UNDER 50 YEARS OLD WITH MYOCARDIAL INFARCTION AND ARTERIAL HYPERTENSION

Abstract

Relevance. Myocardial infarction and its complications in young and middle-aged men with arterial hypertension remains an important problem of modern cardiology. Aim. To evaluate the cardiovascular risk factors structure features in men under 50 years old with arterial hypertension to improve prevention and outcomes. Material and methods. The study included 209 men aged 19-50 years old with type I myocardial infarction, who underwent a standard diagnostic algorithm in the first 48 hours and at the end of the third week of the disease. The patients were divided into two age-matched groups: with arterial hypertension (121 patients, 88 patients without arterial hypertension). A comparative analysis of the frequency of identifying the main and additional cardiovascular risk factors and their parameters were performed in the selected groups. Results. The study group showed more pronounced glycemia (5.6±1.4 mmol/l) than in the control group (5.2±1.3 mmol/l; p=0.04) at the end of the third week of myocardial infarction. In this group, there was a high incidence of obesity (42.1 and 25.0%, respectively; p=0.01), changes in peripheral arteries (86.0 and 3.5%; p<0.0001) and target organ damage , meteorological dependence (31.4 and 9.1%; p=0.0001), impaired peripheral hemodynamics, as well as hereditary burden of vascular pathology (100 and 56.8%; p=0.03). Conclusions. The data obtained suggest a worse long-term prognosis and a greater degree of resistance to treatment in men with arterial hypertension, which must be considered when implementing preventive programs.