[Acute poisoning of an infant by cutaneous application of a local counterirritant and pulmonary antiseptic salve].

J P Dupeyron, F Quattrocchi, H Castaing, P Fabiani
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Abstract

The case of acute poisoning reported here raises the question of the harmlessness of preparations destined for cutaneous application in infants. After describing the method perfected for the identification and estimation of camphor, menthol and thymol in biological material, the authors present the toxicological, clinical and biological arguments in favour of the notion that the cutaneous resorption of these substances was responsible for this acute intoxication in an infant. Particular attention should be paid to poisoning which may result, in the newborn and infant, from the cutaneous application of active substances.

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[因局部使用抗刺激和肺消毒药膏引起的婴儿急性中毒]。
这里报告的急性中毒病例提出了一个问题,即用于婴儿皮肤应用的制剂是否无害。在描述了生物材料中樟脑、薄荷醇和百里香酚的鉴定和估计的完善方法后,作者提出了毒理学、临床和生物学的论点,支持这些物质的皮肤吸收是导致婴儿急性中毒的原因。应特别注意可能导致新生儿和婴儿因皮肤使用活性物质而中毒。
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