Utility and Acceptability of Perskindol Spray and Gel as a Topical Treatment for Musculoskeletal Pain

P. Padungsutt, W. Tassanawipas, Agripino Beng Javier, Paul Nierva
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Abstract

Perskindol (study treatment) is a topical pain treatment in gel or spray form which contains menthol and herbal components. These two open-label, prospective, nonrandomized monadic studies in the Philippines and Thailand investigated the utility and acceptability of the study treatment for musculoskeletal pain. Adults with musculoskeletal pain were advised to use the study gel or spray as needed for up to 7 days. Their usage, perceptions, and response to treatment were assessed by patient diary and structured questionnaire. At study end, patients from both studies generally rated the study treatment higher in terms of ease of use, onset, and duration of pain relief, low potential for skin irritation and overall rating compared with their previous treatment. Differentiation analysis showed that the study treatment addressed patient preferences perceived as important, which were rapid relief of pain and ease of use. These findings suggest that the study spray and gel are useful and acceptable topical treatments for musculoskeletal pain and may be considered in self-directed pain management.
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Perskindol喷雾和凝胶作为局部治疗肌肉骨骼疼痛的效用和可接受性
Perskindol(研究治疗)是一种局部疼痛治疗凝胶或喷雾形式,含有薄荷醇和草药成分。在菲律宾和泰国进行的这两项开放标签、前瞻性、非随机的单一研究调查了研究治疗肌肉骨骼疼痛的效用和可接受性。建议患有肌肉骨骼疼痛的成年人根据需要使用研究凝胶或喷雾长达7天。通过患者日记和结构化问卷评估他们的使用、认知和对治疗的反应。在研究结束时,与之前的治疗相比,两项研究的患者在易用性、疼痛缓解的开始和持续时间、皮肤刺激的可能性低和总体评分方面普遍对研究治疗的评分更高。分化分析表明,研究治疗解决了患者认为重要的偏好,即快速缓解疼痛和易于使用。这些发现表明,研究喷雾和凝胶是有效的和可接受的局部治疗肌肉骨骼疼痛,可以考虑在自我指导的疼痛管理。
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