Low Density Lipoproteins May Actually Be Some Negative Acute Phase Proteins in the Plasma

M. Helvaci, A. Abyad, Lesley Pocock
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Abstract

There were 75 patients in the first and 118 patients in the second groups. Mean age (45.4 versus 47.9 years) and male ratio (53.3 versus 53.3%) were similar in both groups (p>0.05 for both). Smoking (34.6 versus 31.3%), body mass index (27.2 versus 26.7 kg/m2), fasting plasma glucose (119.4 versus 113.0 mg/dL), white coat hypertension (25.3 versus 32.2%), hypertension (10.6 versus 16.1%), and chronic obstructive pulmonary disease (14.6 versus 18.6%) were similar in both groups, too (p>0.05 for all). Although triglycerides (162.7 versus 125.4 mg/dL, p<0.001), diabetes mellitus (DM) (21.3 versus 12.7%, p<0.05), and coronary heart disease (CHD) (20.0 versus 11.0%, p<0.05) were higher, low density lipoproteins (LDL) (105.3 versus 126.2 mg/dL) and HDL (34.1 versus 50.0 mg/dL) were lower in patients with plasma HDL values of lower than 40 mg/dL, significantly (p<0.000 for both).
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低密度脂蛋白实际上可能是血浆中的一些阴性急性期蛋白
第一组75例,第二组118例。两组患者的平均年龄(45.4比47.9岁)和男性比例(53.3比53.3%)相似(p < 0.05)。吸烟(34.6 vs 31.3%)、体重指数(27.2 vs 26.7 kg/m2)、空腹血糖(119.4 vs 113.0 mg/dL)、白皮肤高血压(25.3 vs 32.2%)、高血压(10.6 vs 16.1%)和慢性阻塞性肺疾病(14.6 vs 18.6%)在两组中也相似(p < 0.05)。尽管甘油三酯(162.7 vs 125.4 mg/dL, p<0.001)、糖尿病(21.3 vs 12.7%, p<0.05)和冠心病(20.0 vs 11.0%, p<0.05)较高,但血浆HDL值低于40 mg/dL的患者低密度脂蛋白(LDL) (105.3 vs 126.2 mg/dL)和高密度脂蛋白(34.1 vs 50.0 mg/dL)较低,两者均显著(p<0.000)。
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