SÍNTESE E CARACTERIZAÇÃO DE MEMBRANAS DE NORBIXINA, ETILENOGLICOL E PHB PARA APLICAÇÕES EM BIOMATERIAIS

Medicina: A ciência e a tecnologia em busca da cura 3 Pub Date : 2021-12-20 DOI:10.22533/at.ed.96021201220

Rayssilane Cardoso de Sousa, L. Carvalho, Antônio Luíz Martins Maia Filho, Vicente Galber Freitas Viana

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Abstract

Biomaterials are substances of synthetic or natural origin that replace and / or stimulate biological systems that no longer have their functions, for example: the restoration of tissue functions. In view of the antioxidant potential of norbixin (dicarboxylic carotenoid found in Bixa orellana L.) and from the biodegradability and biocompatibility of polyhydroxybutyrate (PHB) (natural polymer synthesized from bacteria) and ethylene glycol, it was aimed at preparing membranes of PHB and PHB/Norbixin/ethylene glycol, for healing purposes, and characterize them through Fourier transformed infrared spectroscopy (FTIR), x-ray fluorescence (FRX), Thermogravimetry Analytics(TGA and Differential Scanning Calorimetry (DSC). It was obtained homogenous membranes with spectra of the characteristic functional groups and good thermal stability of the samples. The presence of norbixin and the addition of ethylene glycol rather interfere with the physicochemical characterization of PHB Key-words: Norbixin. Polyhydroxybutyrate. Ethylene glycol. Polimer. Biomaterials

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用于生物材料的诺比辛、乙二醇和PHB膜的合成与表征

生物材料是一种合成或天然物质，用于替代和/或刺激不再具有其功能的生物系统，例如:组织功能的恢复。考虑到去氧比辛(bibixin) (Bixa orellana L.中发现的二羧基类胡萝卜素)的抗氧化潜力，以及聚羟基丁酸盐(PHB)(细菌合成的天然聚合物)和乙二醇的生物降解性和生物相容性，旨在制备PHB和PHB/去氧比辛/乙二醇膜，用于愈合目的，并通过傅里叶变换红外光谱(FTIR)、x射线荧光(FRX)、热重分析(TGA)和差示扫描量热法(DSC)。得到了具有特征官能团光谱的均匀膜，样品具有良好的热稳定性。苯并菌素的存在和乙二醇的加入对苯并菌素的理化性质有较大的干扰。Polyhydroxybutyrate。乙二醇。Polimer。生物材料

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Medicina: A ciência e a tecnologia em busca da cura 3

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