The use of clonazepam in the treatment of tic douloureux (a preliminary report).

B Chandra
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Abstract

Results are reported of a preliminary trial with clonazepam in 19 patients with trigeminal neuralgia refractory to carbamazepine treatment. In this series of patients, 13 (68.4%) showed excellent or good improvement. No serious side-effects were seen. The pharmacology and mechanism of action of clonazepam are discussed. It is suggested that patients with trigeminal neuralgia, who do not respond to carbamazepine, should be given clonazepam before surgery is considered.

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氯硝西泮治疗抽动性杜鲁流(初步报告)。
结果报告了初步试验氯硝西泮对卡马西平治疗难治性三叉神经痛的19例患者。在这组患者中,13例(68.4%)表现出优异或良好的改善。没有发现严重的副作用。讨论了氯硝西泮的药理作用和作用机制。建议卡马西平无效的三叉神经痛患者在考虑手术前给予氯硝西泮。
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