The Goeppingen Genereactor For Dna-Analysis

Mechtilde Schäfer, Matthias Walz, R. Stein, Lars Vollmer, Günther Schuster, A. Foitzik
{"title":"The Goeppingen Genereactor For Dna-Analysis","authors":"Mechtilde Schäfer, Matthias Walz, R. Stein, Lars Vollmer, Günther Schuster, A. Foitzik","doi":"10.1142/S1465876303001848","DOIUrl":null,"url":null,"abstract":"So far the verification of specific bacteria is time consuming and costly. The reason is the neccessity for highly specialised laboratory equipment and the requirements regarding clean-room facilities ensuring environments free of any germs. Additionally growing bacteria in equivalent petri dishes may require quite some time until a reasonable number is grown sufficient for further evaluation. For many bacteria and even viruses alternative processes for multiplication have been developed, basically relying on the so called Polymerase Chain Reaction (PCR). We developed the Goeppingen GeneReactor, a microsized system (MEMS) for PCR as a low cost device, that can be used without any clean-room facilities, while additionally a device for electrophoresis is added as a tool for analysis. Thus this system can be used as a throw analysis tool, i.e. specimen containig the required bacteria or viruses could be preparated and investigated in every physician's pratice. It should be noted, that even tiny amounts of st...","PeriodicalId":331001,"journal":{"name":"Int. J. Comput. Eng. Sci.","volume":"6 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2003-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Int. J. Comput. Eng. Sci.","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1142/S1465876303001848","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

So far the verification of specific bacteria is time consuming and costly. The reason is the neccessity for highly specialised laboratory equipment and the requirements regarding clean-room facilities ensuring environments free of any germs. Additionally growing bacteria in equivalent petri dishes may require quite some time until a reasonable number is grown sufficient for further evaluation. For many bacteria and even viruses alternative processes for multiplication have been developed, basically relying on the so called Polymerase Chain Reaction (PCR). We developed the Goeppingen GeneReactor, a microsized system (MEMS) for PCR as a low cost device, that can be used without any clean-room facilities, while additionally a device for electrophoresis is added as a tool for analysis. Thus this system can be used as a throw analysis tool, i.e. specimen containig the required bacteria or viruses could be preparated and investigated in every physician's pratice. It should be noted, that even tiny amounts of st...
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
用于dna分析的goepingen发生器
到目前为止,对特定细菌的验证既耗时又昂贵。其原因是需要高度专业化的实验室设备和有关洁净室设施的要求,以确保没有任何细菌的环境。此外,在等效的培养皿中培养细菌可能需要相当长的时间,直到培养出足够的数量以进行进一步评估。对于许多细菌甚至病毒来说,已经开发出了增殖的替代过程,基本上依赖于所谓的聚合酶链式反应(PCR)。我们开发了Goeppingen GeneReactor,这是一种用于PCR的微尺寸系统(MEMS),作为一种低成本设备,可以在没有任何洁净室设施的情况下使用,同时还增加了一种电泳设备作为分析工具。因此,该系统可作为一种投掷分析工具,即在每个医生的实践中都可以制备和调查含有所需细菌或病毒的标本。应该指出的是,即使是少量的……
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
The Hybrid Boundary Element Method Applied to Problems of Potential Theory in Nonhomogeneous Materials On the Poisson's Ratio Effect on Mixed-mode Stress Intensity Factors and T-stress in Functionally Graded Materials Guest Editorial: Modeling of Functionally Graded Materials Effect of a Graded Interface on a Crack Approaching at an Oblique Angle Efficient Reformulation of the Thermal Higher-order Theory for Fgms with Locally Variable Conductivity
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1