ADHD Treatment in Primary Care: Demographic Factors, Medication Trends, and Treatment Predictors

Tanya S Hauck, C. Lau, Laura Wing, P. Kurdyak, K. Tu
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引用次数: 41

Abstract

Background: The aim of this study is to determine the prevalence and characteristics of youth with attention-deficit hyperactivity disorder (ADHD) in Ontario, Canada, and to determine the predictors of psychotropic medication prescriptions in youth with ADHD. Method: This is a cross-sectional retrospective chart abstraction of more than 250 000 medical records from youth aged 1 to 24 years in a large geographical region in Ontario, Canada, linked to population-based health administrative data. A total of 10 000 charts were randomly selected and manually reviewed using predetermined criteria for ADHD and comorbidities. Prevalence, comorbidities, demographic indicators, and health service utilization characteristics were calculated. Predictors of treatment characteristics were determined using logistic regression modelling. Results: The prevalence of ADHD was 5.4% (7.9% males, 2.7% females). Youth with ADHD had significant psychiatric comorbidities. The majority (70.0%) of ADHD patients received prescriptions for stimulant or nonstimulant ADHD medication. Antipsychotic prescriptions were provided to 11.9% of ADHD patients versus 0.9% of patients without ADHD. Antidepressant prescriptions were provided to 19.8% versus 5.4% of patients with and without ADHD, respectively. Predictors of antidepressant prescriptions were increasing age (odds ratio [OR], 1.14; 95% confidence interval [CI], 1.07 to 1.21), psychiatric consultation (OR, 2.04; 95% CI, 1.16 to 3.58), and diagnoses of both anxiety and depression (OR, 18.4; 95% CI, 8.03 to 42.1), whereas the only predictor of antipsychotic prescriptions was psychiatric consultation (OR, 3.85; 95% CI, 2.11 to 7.02). Conclusions: Youth with ADHD have more psychiatric comorbidities than youth without ADHD. The majority of youth with ADHD received stimulant medications, and a significant number received additional psychotropic medications, with psychiatric consultation predicting medication use.
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初级保健中的ADHD治疗:人口统计学因素、用药趋势和治疗预测因素
背景:本研究的目的是确定加拿大安大略省青少年注意力缺陷多动障碍(ADHD)的患病率和特征,并确定ADHD青少年精神药物处方的预测因素。方法:这是一个横断面回顾性图表抽象超过25万的医疗记录从1至24岁的青年在安大略省,加拿大的一个大的地理区域,与人口为基础的卫生管理数据。总共有10000张图表是随机选择的,并使用预先确定的ADHD和合并症标准进行人工审查。计算患病率、合并症、人口统计指标和卫生服务利用特征。使用逻辑回归模型确定治疗特征的预测因子。结果:ADHD患病率为5.4%(男性7.9%,女性2.7%)。青少年ADHD患者有明显的精神合并症。大多数(70.0%)ADHD患者接受了兴奋剂或非兴奋剂的ADHD药物处方。11.9%的ADHD患者和0.9%的非ADHD患者开了抗精神病药处方。分别有19.8%和5.4%的ADHD和非ADHD患者获得抗抑郁药处方。抗抑郁药处方的预测因子为年龄增加(优势比[OR], 1.14;95%可信区间[CI], 1.07 ~ 1.21),精神科咨询(OR, 2.04;95% CI, 1.16 - 3.58),以及焦虑和抑郁的诊断(OR, 18.4;95% CI, 8.03 - 42.1),而抗精神病药物处方的唯一预测因子是精神病咨询(OR, 3.85;95% CI, 2.11 ~ 7.02)。结论:患有ADHD的青少年比没有ADHD的青少年有更多的精神合并症。大多数患有多动症的青少年接受了兴奋剂药物治疗,还有相当多的人接受了额外的精神药物治疗,精神病咨询可以预测药物的使用。
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