{"title":"Radiation sensitizing effect of diamide on human cells cultivated in vitro.","authors":"E O Pettersen, R Oftebro, T Brustad","doi":"10.3109/02841867609131980","DOIUrl":null,"url":null,"abstract":"Human cells of line NHIK 3025 were irradiated suspended in growth medium (E2a) in absence and presence of diamide under aerobic and extremely hypoxic (less than 4 ppm O2) conditions. A sensitizing effect of diamide was found for doses exceeding 8 Gy (800 rad) on cells irradiated under extremely hypoxic conditions in presence of diamide of concentration 200 micrometer, whereas no significant effect was observed for 20 micrometer.","PeriodicalId":7139,"journal":{"name":"Acta radiologica: therapy, physics, biology","volume":"15 6","pages":"551-9"},"PeriodicalIF":0.0000,"publicationDate":"1976-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867609131980","citationCount":"4","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta radiologica: therapy, physics, biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3109/02841867609131980","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 4
Abstract
Human cells of line NHIK 3025 were irradiated suspended in growth medium (E2a) in absence and presence of diamide under aerobic and extremely hypoxic (less than 4 ppm O2) conditions. A sensitizing effect of diamide was found for doses exceeding 8 Gy (800 rad) on cells irradiated under extremely hypoxic conditions in presence of diamide of concentration 200 micrometer, whereas no significant effect was observed for 20 micrometer.
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