Studies on experimental coronary insufficiency. II. Effects of beta-adrenergic blocking agent (propranolol) on metabolic response to adrenaline and noradrenaline in dogs with coronary constriction.

O Iimura, C Wakabayashi, T Kobayashi, T Shoji, S Yoshida, M Miyahara
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Abstract

To obtain further information on the mechanism by which catecholamines produce myocardial ischemia, the effects of propranolol on metabolic and mechanical responses to adrenaline or noradrenaline were investigated in coronary-constricted dogs. Propranolol suppressed the myocardial ischemia produced by noradrenaline and adrenaline in dogs with moderate coronary constriction.

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实验性冠状动脉不全的研究。2-肾上腺素能阻滞剂(心得安)对冠状动脉收缩犬肾上腺素和去甲肾上腺素代谢反应的影响。
为了进一步了解儿茶酚胺导致心肌缺血的机制,我们研究了心得安对冠状动脉收缩犬对肾上腺素或去甲肾上腺素的代谢和机械反应的影响。心得安抑制中度冠状动脉狭窄犬去甲肾上腺素和肾上腺素引起的心肌缺血。
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