Ultrastructural change in myocardium subsequent to ischemic cardioplegia "no-reflow phenomenon".

M Sunamori, R Hatano, T Suzuki, N Yamamoto, T Tsukuura, T Yamada, T Kumazawa, M Nakagawa, T Sunaga
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引用次数: 0

Abstract

Mongrel dogs were subjected to cardiopulmonary bypass with hemodilution and to normothermic anoxic arrest for 30 minutes, to study the subepicardial and the subendocardial myocardial ultructure and the DPTI/TTI ratio. "No-reflow phenomenon" was demonstrated in the myocardium after cardiopulmonary bypass, associated with normothermic anoxic arrest. No-reflow phenomenon was a contributing factor to subendocardial ischemia in the normotrophied ventricle after open-heart surgery. Severe hemodilution with hemoglobin less than 5.0 g% resulted in irreversible damage in both myocardial layers.

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缺血性心脏骤停后心肌超微结构改变的“无血流现象”。
采用血液稀释体外循环和常温缺氧停搏30 min,观察心外膜下、心内膜下心肌结构及DPTI/TTI比值。体外循环术后心肌出现“无血流现象”,伴有常温缺氧骤停。无血流现象是心内直视手术后正常营养心室心内膜下缺血的一个因素。血红蛋白低于5.0 g%的严重血液稀释导致两层心肌的不可逆损伤。
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